Psoriasis is an autoimmune condition that causes inflamed, scaly skin patches. People with psoriasis are more likely to develop certain skin infections. This increased risk is due to a combination of factors, including damage to the skin barrier, immune system dysfunction, and the use of immunosuppressive medications.

It’s important to identify and treat skin infections early, as they can lead to complications. However, because psoriasis and skin infections can cause similar symptoms, it’s not always easy to tell them apart. Recognizing the warning signs can help ensure timely medical treatment.

Why Psoriasis Can Increase the Risk of Skin Infections

Although anyone can get a skin infection, having an autoimmune condition like psoriasis may increase that risk. Several reasons explain this connection.

Skin Barrier Damage

Healthy skin provides a protective barrier that prevents harmful microorganisms from entering the body. Psoriasis disrupts this barrier, making the skin more vulnerable to bacteria, viruses, and fungi. Scratching itchy psoriasis patches can further break the skin, creating open wounds that allow infections to develop.

Immune System Dysfunction

Psoriasis is an autoimmune condition where the immune system attacks healthy skin cells, leading to inflammation and rapid skin turnover. Since the immune system is already overactive and misdirected, its ability to fight real infections may be compromised, leaving the body more vulnerable.

Medications

Some psoriasis treatments, especially biologics, suppress parts of the immune system to reduce inflammation. While effective for managing psoriasis, these medications can also raise the risk of serious infections, including those affecting the skin, lungs, or digestive tract.

Other Health Conditions

People with psoriasis often have other health issues like diabetes, obesity, or metabolic syndrome. These conditions also impair immune function, contributing to an increased risk of severe skin infections.

What Are the Signs of a Skin Infection?

Skin infections occur when bacteria, viruses, fungi, or parasites invade the body. Symptoms vary based on the type of infection but commonly include:

  • Swelling

  • Itchiness

  • Redness or discoloration

  • Pain or tenderness

  • Pus or drainage

  • Rash or raised bumps

  • Warmth around the affected area

Some skin infections can resemble psoriasis flares. For example, pustular psoriasis and skin infections may both cause pus-filled bumps. However, infections may also be accompanied by fever, pain, or spreading redness.

What Types of Skin Infections Are You at Greater Risk For?

People with psoriasis may be more likely to develop several types of skin infections, such as:

Staph Infections

Staphylococcus aureus bacteria naturally live on the skin, but in people with psoriasis, they are often present in higher amounts. This increases the risk of infection, particularly if the skin barrier is broken.

MRSA (Methicillin-Resistant Staphylococcus Aureus)

MRSA is a dangerous form of staph infection that resists many antibiotics. People with psoriasis, especially those who have been hospitalized, are at higher risk for MRSA skin infections.

Fungal Infections

Psoriasis increases the risk of Candida overgrowth, leading to infections like thrush, vaginal yeast infections, and diaper rash. Studies show higher amounts of Candida on the skin of individuals with psoriasis.

Impetigo

Impetigo is a contagious bacterial skin infection. Psoriasis-damaged skin makes it easier for bacteria such as Staphylococcus or Streptococcus to enter and cause infection.

Infections Can Trigger Psoriasis

Interestingly, the relationship between psoriasis and infections goes both ways. While psoriasis increases the risk of skin infections, certain infections can also trigger psoriasis flares. Conditions like strep throat, bronchitis, and ear infections can cause psoriasis to worsen a few weeks after the infection occurs.

How To Prevent Skin Infections When You Have Psoriasis

Managing psoriasis and minimizing exposure to germs can help reduce the risk of skin infections. Tips for prevention include:

  • Avoid injuring your skin (cuts, burns, insect bites)

  • Identify and avoid psoriasis triggers (stress, harsh weather, certain medications, smoking, alcohol)

  • Resist scratching itchy patches by using moisturizers and cold compresses

  • Keep your hands clean with frequent handwashing

  • Clean and cover any cuts or wounds

  • Do not share personal items like towels or razors

  • Wear loose-fitting, breathable clothing

  • Talk to your doctor about any additional health risks (e.g., diabetes) that may raise your infection risk

When To See a Healthcare Provider

Skin infections are one of the most common conditions treated in outpatient healthcare settings. If you have psoriasis and notice new or worsening skin symptoms—especially if accompanied by pain, fever, or pus—see a healthcare provider promptly. If you’re unsure whether symptoms are from psoriasis or an infection, medical evaluation is essential.

Delayed treatment can lead to complications such as gangrene, sepsis, or necrotizing fasciitis. Your provider may perform a skin examination, take a biopsy or swab sample, and run blood tests to determine the type of infection. Treatment may include oral or topical antibiotics, antiviral or antifungal medications, or procedures like draining abscesses.

A Quick Review

Psoriasis can increase your risk of developing infections like MRSA, Candida, and impetigo due to skin barrier damage and immune dysfunction. Infections can also trigger psoriasis flares. Be alert for signs like redness, swelling, pus, and fever. To prevent infection, maintain good hygiene, treat wounds carefully, and manage your psoriasis effectively. Seek medical attention if symptoms arise, as early treatment can prevent serious complications.