The CBD oil industry is booming—and there's no sign of it slowing down. As consumers increasingly turn to natural remedies for stress relief, chronic pain, sleep issues, and overall wellness, cannabidiol (CBD) oil continues to gain traction as a versatile and therapeutic product. Derived from the cannabis plant, CBD offers a wide array of health benefits without the high caused by THC, making it a mainstream wellness solution embraced by millions worldwide.

In this article, we explore the top 10 CBD oil companies in 2024 that are leading the charge globally. These companies are not only driving innovation but also setting the standard in quality, transparency, and customer satisfaction.

CBD Oil Market Overview: A Multi-Billion-Dollar Opportunity

CBD oil, extracted from Cannabis sativa, is used in full-spectrum, broad-spectrum, and isolate forms. Mixed with carrier oils like MCT or hemp seed oil, it's known to support conditions ranging from chronic pain and anxiety to skin issues, epilepsy, and even cardiovascular health.

  • The global CBD oil market was valued at USD 6.24 billion in 2022.

  • It is expected to grow at a compound annual growth rate (CAGR) of 16.0% through the coming years.

  • Drivers of growth include increasing legalization, rising consumer awareness, and broad product diversification into healthcare, personal care, and pet wellness.

However, the market still faces challenges such as regulatory uncertainty and limited consumer education in certain regions.

Top 10 CBD Oil Companies in the World (2024)

1. Medical Marijuana, Inc.

Annual Revenue: USD 20.24 Billion

Pioneering the CBD industry, Medical Marijuana, Inc. was the first publicly traded cannabis company in the U.S. Founded in 2009, it's known for brands like Real Scientific Hemp Oil (RSHO) and Dixie Botanicals. The company remains a leader in innovation, quality assurance, and global expansion. Their product line includes tinctures, capsules, edibles, and topicals, all crafted with a strong emphasis on scientific research and legality.

What Sets Them Apart:

  • First mover in legal CBD space

  • International market presence

  • Rigorous quality control and R&D

2. Cannoid, LLC

Annual Revenue: USD 18.21 Billion

Established in 2016, Cannoid quickly became a CBD market leader with a broad product line featuring CBD oils, topicals, tinctures, edibles, and pet products. Their proprietary extraction techniques, third-party testing, and GMP-certified facilities distinguish them in a crowded field.

What Sets Them Apart:

  • Transparent labeling

  • Eco-friendly packaging

  • Innovative extraction and formulation

3. PharmaHemp

Annual Revenue: USD 2.65 Billion

Based in Europe, PharmaHemp is synonymous with organic farming and premium quality. Since 2011, the company has offered a wide range of full-spectrum and broad-spectrum CBD products supported by extensive third-party lab testing. Their commitment to sustainability and innovative wellness solutions has earned them a loyal customer base globally.

What Sets Them Apart:

  • EU-based production

  • Organic and sustainable sourcing

  • Robust quality assurance processes

4. Isodiol International Inc.

Annual Revenue: USD 84 Million

Founded in 2014, Isodiol is a globally recognized CBD company with a massive product portfolio, including CBD topicals, beverages, skincare, and wellness supplements. They’ve made waves through celebrity partnerships, athlete endorsements, and global distribution deals.

What Sets Them Apart:

  • Celebrity-backed marketing

  • International reach

  • Cutting-edge formulations and delivery systems

5. Gaia Botanics

Annual Revenue: USD 80.4 Million

Gaia Botanics focuses on wellness through nature, offering organically grown, non-GMO CBD oils, edibles, and skincare products. Founded in 2015, they’ve earned customer trust by implementing rigorous third-party testing and producing targeted wellness formulas for stress, sleep, and inflammation.

What Sets Them Apart:

  • Botanical-based approach

  • Clean ingredient standards

  • Specialized wellness blends

6. NuLeaf Naturals, LLC

Annual Revenue: USD 19.4 Million

Since 2014, Denver-based NuLeaf Naturals has specialized in high-potency, full-spectrum CBD oil tinctures and softgels. Their CO2 extraction process and commitment to organic farming practices make them a go-to brand for wellness-conscious consumers.

What Sets Them Apart:

  • Industry-leading full-spectrum products

  • Transparent lab results

  • Focused product line with consistent dosing

7. Joy Organics

Annual Revenue: USD 8.2 Million

Launched in 2018 by Joy Smith, Joy Organics is a fast-growing brand that emphasizes broad-spectrum, THC-free CBD products. From USDA-certified organic tinctures to CBD skincare and gummies, they’ve gained recognition for product purity and customer-first service.

What Sets Them Apart:

  • THC-free, lab-tested formulas

  • Organic certification

  • Strong educational outreach

8. Lazarus Naturals

Annual Revenue: USD 7.2 Million

Founded in 2014, Lazarus Naturals is known for its affordable, high-quality CBD products and veteran-focused discount programs. Their vertically integrated model ensures complete control from farm to shelf, and they’ve expanded into THC-free and organic lines.

What Sets Them Apart:

  • Affordability without sacrificing quality

  • Strong social mission and assistance programs

  • In-house manufacturing and sourcing

9. Freedom Leaf, Inc.

Annual Revenue: USD 5 Million

More than just a CBD company, Freedom Leaf, Inc. also serves as a media platform in the cannabis space. With roots in advocacy, they produce a range of CBD oils while also running Freedom Leaf Magazine—a source of cannabis news and education.

What Sets Them Apart:

  • Dual focus on product and education

  • Market insight through media publishing

  • Advocacy for cannabis industry growth

10. CV Sciences Inc.

Known for their flagship brand PlusCBD™, CV Sciences has been instrumental in shaping the commercial CBD market in the U.S. With a strong scientific backing, they deliver capsules, drops, sprays, and gummies that are widely available in retail and e-commerce channels.

What Sets Them Apart:

  • Leader in clinical research

  • Recognized by healthcare professionals

  • National retail footprint

Final Thoughts

The CBD oil market in 2025 is thriving, fueled by rising demand, increasing legality, and a consumer base that’s more informed and health-conscious than ever. Whether you’re a newcomer to CBD or a seasoned user, these ten companies represent the best in quality, transparency, and innovation. They’re not only shaping the current landscape but also setting the foundation for the future of wellness through CBD.